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Richard Bergland
51 quotes
“Whatever the cerebellum is doing, it’s doing a lot of it.”
Richard Bergland first seen 2013 wikiquote, CC BY-SA 4.0 source
Recorded in: As quoted by Christopher Bergland "How is the Cerebellum Linked to Autism Spectrum Disorders?" Psychology Today (Sept 2013) referring to the cerebellum's containing 50% of the brain's neurons in only 10% of the volume
“Amending your own mind is very, very satisfying… amending other people's minds is a fruitless, unsatisfying effort.”
Richard Bergland first seen 1968 wikiquote, CC BY-SA 4.0 source
Recorded in: As quoted in "Van Wagenen Fellowship Richard M. Bergland 1968 Oxford University," American Association of Neurological Surgeons (2004)
“Neurosurgery can be learned... neurosurgery cannot be taught.”
Richard Bergland first seen 1968 wikiquote, CC BY-SA 4.0 source
Recorded in: As quoted in "Van Wagenen Fellowship Richard M. Bergland 1968 Oxford University," American Association of Neurological Surgeons (2004)
“Not all ideas of the ideas that pass from one brain to another brain... are good ideas; some are mistakes. These I call 'mismemes'.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The existing paradigm about the brain has ceased to function adequately.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The belief that electricity, the fourth of the modern forces, is the stuff of thought has permeated brain science since the late 1700s. ...while the brain was regarded as 'dry', all other organs were conceived as 'wet'. Doubtless the study of brain electricity helped in understanding the internal circuits of the brain, but it solved few problems of brain disease.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Brain/body relationships might depend upon a chorus of individual hormones... which are released together to sing hormonal harmonies to the body.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The double-think of modern science—'Molecules shape the body, but electricity shapes the mind'—ends abruptly with the realization that regulatory hormones control both brain and body functions.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Pattern recognition is the sine qua non of the genetic code... pattern recognition underlies all immunology... pattern recognition is basic to all the hormone/hormone receptor interactions of cell regulation; and pattern recognition is the highest form of thought. It is the synchrony, the synergism and the spatial juxtaposition of whirling hormonal forces that give life to the human soul. Is this molecular maelstrom divine? I think so: it creates life, it is ubiquitous, it cannot be broken apart, it cannot be contained, it cannot be copied, it is eternal.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Regulatory messages or hormones flow from specific regions of the brain to specific glands within 'hollow' nerve fibres exactly as Erasistratus, Galen and Descartes had taught.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The science of neuroendocrinology—the brain-to-pituitary link that was discerned by [Joe] Hinsey, [George] Wislocki, du Vigneaud, and [Geoffrey] Harris—is dependent upon hormones flowing within nerve axons. This phenomenon, axonal flow, was first noted by Ernst and Barta Scharrer... For many decades it was assumed that axonal flow was always 'down'... away from the brain.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Molecules move not only from the brain to the endocrine system but also from the endocrine system, indeed, from all parts of the body to the brain.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Every organ is a hormone-producing gland.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Central to the paradigm that the mind is modulated by hormones is the recognition that the stuff of thought is not caged in the brain but is scattered all over the body; regulatory hormones are ubiquitous.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Gone are the days when scientists believed one hormone was made by one gland. Insulin, for example... is made in other surprising places, like the brain, and even by tiny one-cell organisms without a pancreas.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The neatly integrated paradigm for brain water... was derived from experiments done by Walter Dandy... Most brain scientists and brain physicians honour the Dandy paradigm as a navigator honours the North Star. ...yet new scientific evidence makes it difficult, if not impossible, to accept... It is a mismeme; the experimental facts no longer allow it to be 'true', and we need a paradigm switch.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Dandy's experiments were done in the fast lane of science... performed with no control animals, with no record of the number of animals operated on, with no regard for inter-species variability, with no record of the time base, with no histological correlation, with no attempt to quantify the differences and with no involvement with a neutral scientist.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“If the powerful hormone vasopressin, or ADH, is injected into the blood, the body will retain water. If ADH is injected into the ventricle the opposite happens: the body loses water.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Those at the top in brain science gained their pedestals by knowing more and more about less and less.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Few would have predicted that the discovery of the circulation of the blood would have changed the way philosophers view the world, theologians conceive of God, or astronomers look at the stars, yet all of that happened.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“If the question, 'Why is the heart hollow?', had a profound impact on all intellectual disciplines, would you expect any less of the question, 'Why is the brain hollow?”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“In the past decade, as regulating hormones have been found throughout the body, the soul has lost its home. It is scattered everywhere—in the brain, the gut, the ovary, the pituitary and the adrenal; if paracrinologists are correct, every cell contains the well-chiselled molecules that give life to the soul and guidance to the mind.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“It would be easier... if all animals spoke the same endocrine language, for then correlations made in the laboratory could be quickly moved to the bedside. Unfortunately, such is not the case. The hormone prolactin, for example, has at least seventy-eight different functions in seventy-eight different species”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The brain has all the characteristics of a gland except one—leaky capillaries—the sturdy brain capillaries are collectively called the 'blood-brain-barrier'. This barrier can easily be demonstrated by injecting a blue dye into an animal; every other organ (except the testicle) turns blue, but the blood-brain barrier keeps the brain as white as snow.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“As hormonal amplification is the hallmark of all of the brain-to-gland relationships of neuroendocrinology, hormonal deamplification is the hallmark of all gland-to-brain relationships of endocrine neurology. This is the fundamental difference between the two sciences.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Some kinds of hormones, the 'steroids', pass readily into the brain, but the 'peptide' hormones produced by the pituitary, the gut, and any other glands do not easily pass through the walls of brain capillaries.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The brain remains silently separated from the noisy endocrine consequences.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The measurement of hormones in the bloodstream of patients will not reflect the endocrine activity of the brain.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The greatest array of brain hormones is found in the ventricle, not in the spinal fluid.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“In decades to come ventricular catheterization performed to measure hormone concentrations will become as routine as the measurement of lumbar 'pressure' is today.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The ventricles of the human brain... are filled with hormones, and until the hormones swimming in these oceans are dredged out, countless millions of our fellows will remain with brain illnesses that can be neither understood nor treated. Many of their hormone-hungry brains may be fixed as easily as hormone-hungry bodies are fixed with thyroid hormone, insulin, oestrogen and testosterone, but that work cannot begin until cause and effect relationships between brain hormones and brain diseases have been established.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Miracles of inner healing are everyday occurrences.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The brain is a gland of unity: the brain is one with the body.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Neurosurgeons perform ventricular taps with great frequency. …While this is not something to be done lightly, the risks are no greater than those for cardiac catheterization.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Twenty years from now, the disease, 'presenile dementia' will be understood as well as diabetes is today.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“If a 'memory peptide' could be found to be deficient in patients with dementia, these patients could be treated in the same way that patients with diabetes are treated with insulin.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Scientists have mastered the techniques of hormone analysis, measurement and manufacture. What is lacking is the correlation between a specific brain disease and a specific brain hormone. …these correlations can only come from a medical team of co-operating physicians.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Animal experiments have confirmed the necessity of delivering hormones into the ventricle: the powerful hormone endorphin does not change behaviour if it is given intravenously; vasopressin will improve memory in animals only if it given into the ventricles; insulin given through the bloodstream does not control appetite but it is the best hormone for such control if given into the brain; and bombesin... only stops stomach ulceration if given into the brain.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Genetic engineers are powerless in all of this without some cooperative effort from people working in allied fields.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Already in animals, some gland-like cells have been transplanted from the adrenal gland into the brain, where they not only survive but continue their secretions.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“By placing… cell-containing soup in bullet-shaped cell cages formed out of permeable plastics, a single population of cells can be introduced into the brain. ...the hormones that are produced by the cells make their way... into the brain. ...'artificial glands' …with no fear of cell migration.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“As it is possible that the memory loss of senile dementia may stem from a deficiency of 'memory peptide', obesity may result from a deficiency of either bombesin, somatostatin, cholecystokinen, gastrin, or insulin.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Despite the evidence that ventricular hormones do not make their way out of the ventricle, the presence of large ventricles in many schizophrenic patients, and the ability of two-dimensional gels to provide a profile of peptides in the ventricle, not a single catheter has been placed into the ventricle of a schizophrenic patient to measure the peptides in the ventricle. ...There is no animal model for this disease, the answer can only come from human studies.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Many endocrine diseases of the body entail the production of 'crooked molecules'—molecules that are made in the wrong way by the cell. It is fairly common for a cancer cell to begin the production of a 'crooked' hormone that evokes dramatic changes in other body functions.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Electroconvulsive therapy, or ECT, is the best therapy for unipolar depression that exists. ...they have found that the smile will return to the face of the patient on the very same day that cortisol dynamics return to normal.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“During electroconvulsive therapy the blood-brain barrier is opened and during the time that it remains open there are heroically high levels of circulating pituitary hormones. Thus there is every reason to believe that... it delivers hormones to the brain...”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Despite the effectiveness of electroconvulsive therapy... it may cause long-lasting problems with short-term memory. …Yet despite the protests, the ability of cortisol studies to identify patients who will benefit from ECT guarantees that more patients will receive it.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Somehow the same nurses, physicians, administrators and legal ombudsmen who prevented the study of the ventricular fluid of a patient with senile dementia, or obesity, or depression, or schizophrenia, because of the risks, will encourage diagnostic tests and therapy for patients with epilepsy that are far more destructive and immutable than the measurement and manipulation of hormones in the ventricle.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“The hormonal genies that have lived unnoticed in the brain since humankind began have escaped; there is no way that they can be put back.”
Richard Bergland wikiquote, CC BY-SA 4.0 source
“Physicians and scientists will measure brain hormones—in ventricular fluid and elsewhere—will link these to specific diseases, and will devise space-age techniques to restock the mind's hormonal pantries. The only question is, When?'”
Richard Bergland wikiquote, CC BY-SA 4.0 source